A large swath of Indiana, including Fishers, will see snow begin around 1am Wednesday morning and continue most of the day.  Expect 4-8 inches of snow with winds gusting up to 35 miles-per-hour.  The National Weather Service has issued a Winter Storm Warning, which can be seen below:

...WINTER STORM WARNING IN EFFECT FROM 1 AM TO 7 PM EST
WEDNESDAY...

* WHAT...Heavy snow expected. Total snow accumulations of 4 to 8
  inches. Winds gusting as high as 35 mph.

* WHERE...Portions of central Indiana.

* WHEN...From 1 AM to 7 PM EST Wednesday.

* IMPACTS...Travel could be very difficult. The hazardous
  conditions could impact the morning or evening commute.

PRECAUTIONARY/PREPAREDNESS ACTIONS...

If you must travel, keep an extra flashlight, food, and water in
your vehicle in case of an emergency.